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Laxatives

This factsheet is for people who would like information about taking laxatives.

Laxatives are medicines that relieve constipation (difficulty with bowel movements). They are one of the most popular types of over-the-counter remedies. Each year in the UK we spend around £50 million on laxatives in shops and pharmacies.

Why would I take them?

Your doctor may advise you to take laxatives if you have constipation, especially if you have another condition that straining to defaecate can make worse, for example:

  • angina
  • piles (haemorrhoids)
  • a painful tear in the skin round the anus (anal fissure)

Laxatives can also be helpful for people with constipation caused by prescription medicines (eg codeine) or by illness, in older people who are constipated because of reduced mobility, and to help get rid of worms. They are also prescribed to clear the bowel before surgery or for colonoscopy, a test for looking inside the bowel.

Changes in bowel movements can sometimes indicate more serious conditions. You should talk to your doctor if you are losing weight or if you notice blood in your faeces.

What are the main types?

Laxatives are medicines that work on the bowel to relieve constipation. There are several types of laxative that you can buy without a prescription. The main ones are:

  • bulk-forming laxatives, such as bran and ispaghula husk
  • osmotic laxatives, such as magnesium salts and lactulose
  • stimulant laxatives, such as senna and glycerol suppositories

How do laxatives work?

Each type of laxative works in a different way to help relieve or prevent constipation.

  • Bulk-forming laxatives work by softening and increasing the amount of your faeces - the fibre in the bran or isphagula husk "bulks out" the faeces. This then encourages your bowels to move and push the faeces out.
  • Osmotic laxatives work by increasing the amount of water that stays in the faeces as they pass through your intestines. This makes them softer and easier to pass.
  • Stimulant laxatives work by speeding up the movements of your intestines.

Which laxative should I take?

Bulk-forming laxatives are good for people who have small, hard faeces and can't increase the amount of natural fibre they eat. This includes people with colostomy or ileostomy bags, piles, or anal fissures.

The osmotic laxative lactulose can take 48 hours to work. Make sure you drink a normal amount of fluids while taking these medicines.

Stimulant laxatives are helpful if the bowel is full and a bulk-forming laxative is not suitable for you.

How to take laxatives

You can buy each of the three basic types of laxatives without a prescription.

Bulk-forming laxatives come as powders, granules or tablets. You need to take these with plenty of fluids. The full effect of these medicines can take several days of treatment.

Osmotic laxatives come as powders, liquids or enemas. The full effect of these medicines can take several days of treatment.

Stimulant laxatives come as tablets, suppositories, capsules, liquids and enemas. Stimulant laxatives such as senna work within eight to 12 hours, so you should take them at night for an effect the next morning. You should start with a low dose and build up gradually until you feel comfortable when you have a bowel movement.

You should generally try a bulk-forming laxative (eg bran) first. Then move on to try an osmotic laxative if this doesn't work. It's best to only take the stimulant laxatives if you have already tried changing your diet (eg eating more fibre) and the other types of laxatives, and these have not worked.

Generally, laxatives should only be used occasionally. Once your bowel movements are back to normal, you should keep them regular by eating a balanced diet with plenty of fluids and fibre.

You shouldn't give laxatives to children unless your doctor has prescribed them.

Always read the patient information leaflet that comes with your medicine.

Special care

Check with your doctor or pharmacist before taking a laxative if:

  • you are pregnant or breastfeeding
  • you know that your kidneys or liver are not working properly
  • you have an inflammatory bowel disease such as ulcerative colitis

Side-effects

Common side-effects with the bulk-forming laxatives are wind and a swollen abdomen. Rarely, they can also block the intestine.

Osmotic laxatives can cause wind, cramps and discomfort in the abdomen. You may also become dehydrated.

Stimulant laxatives can cause stomach pains and cramping, and too large a dose can cause diarrhoea.

Interactions with other medicines

Check with your doctor or pharmacist before you take any other medicines or herbal remedies at the same time as a laxative.

Names of common laxatives

Examples of the main types of laxatives are shown in the table.

The generic name is the chemical name of a medicine. If a manufacturer has rights over a medicinal compound, it is given a brand name. Often there is more than one brand name associated with a generic name.

Generic names are normally written with a lower-case initial letter and brand names normally start with an upper-case letter.

There are many different products marketed for constipation. Some have more than one ingredient, or different ingredients sold under the same brand name. Ask your pharmacist for advice.

Generic names Examples of common brand names

Bulk-forming laxatives

bran

ispaghula husk

Fibrelief, Fybogel, Isogel, Ispagel Orange, Regulan

methylcellulose

Celevac

sterculia

Normacol

Stimulant laxatives

bisacodyl

Dulco-lax tablets and suppositories

docusate sodium

Dioctyl, Docusol

glycerol

Glycerin suppositories

senna

Ex-lax, Senokot, Nylax

sodium picosulfate

Laxoberal, Dulco-lax

Osmotic laxatives

lactulose

Regulose

macrogols

Idrolax, Movicol

magnesium salts

Milk/cream of Magnesia, Epsom Salts, Original Andrews Salts

phosphates

Carbalax, Fleet enema, Fletchers' Phosphate Enema

sodium citrate

Microlette, Micralax, Relaxit

Further information

Sources

  • Rang HP, Dale MM, Ritter JM. Pharmacology. 5th ed. London: Churchill Livingstone. 2003
  • Laxatives. British National Formulary 2006. 51:57

Published by Bupa's health information team, healthinfo@bupa.com, February 2007.

 

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